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KMID : 0363420110250020111
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Journal of Korean Oriental Pediatrics
2011 Volume.25 No. 2 p.111 ~ p.120
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Estimated Factors and Clinical Characteristics of Children Diagnosed with Idiopathic Precocious Puberty
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Kim Ki-Hoon
Shin Dong-Gil
Kim Dae-Hyun
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Abstract
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Objectives: The purpose of this study is to estimate genetic and environmental factors, which can affect Idiopathic true Precocious puberty, and to evaluate the clinical and endocrinologic characteristics.
Methods: Retrospective and Comparative analysis of 76 children (72 girls and 4 boys) has been diagnosed with idiopathic true precocious puberty, and treated with GnRHa from December 2008 to July 2011.
Results: 1. The Average chronological age (CA. yr) of children diagnosed with idiopathic true precocious puberty was (girls), (boys). 2. The Average height & weight percentile (%ile) of the girls diagnosed with idiopathic true precocious puberty was , . 3. The girls’ mothers have diagnosed with idiopathic true precocious puberty, and they were shorter than the average. This shows that mother’s small height and idiopathic true precocious puberty are closely related to each other. 4. BMI percentile (%ile) of girls diagnosed with idiopathic true precocious puberty was . 23.6% of children were diagnosed with overweight or obesity. This result shows that obesity and idiopathic true precocious puberty are proportionally related. 5. Birth weights (kg) of the children diagnosed with idiopathic true precocious puberty were (girls), (boys). 8.3% of children were diagnosed with Intrauterine growth retardation. 6. The Average bone ages (BA. yr) of the children diagnosed with idiopathic true precocious puberty were (girls), (boys). The Average BA-CA was (girls), (boys). 7. The Average predicted adults’ height (PAH. cm) of the children diagnosed with idiopathic true precocious puberty was (girls), (boys). The Average MPH-PAH was (girls), (boys). 8. 23.6% of the children treated with GnRHa were co-treated with Growth Hormone.
Conclusions: Estimated factors which cause Idiopathic true precocious puberty are mother’s small height, obesity, and Intrauterine growth retardation. However, the studies of Oriental Medicine for Idiopathic true precocious puberty were lacking. Further clinical and experimental researches are needed.
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KEYWORD
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Precocious puberty, Idiopathic true precocious puberty
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